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Reduced Expression of Cyclin-dependent Kinase Inhibitor p27Kip1 in Feline Lymphoma

✍ Scribed by Madewell, B.; Griffey, S.; Walls, J.; Gandour-Edwards, R.


Book ID
124157648
Publisher
American College of Veterinary Pathologists
Year
2001
Tongue
English
Weight
656 KB
Volume
38
Category
Article
ISSN
0300-9858

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The p27 Kip1 protein is a negative regulator of the cell cycle and a potential tumor suppressor gene. Reduced expression of the p27 Kip1 protein has been reported in several human tumors and has been associated with higher tumor grade and increased mortality in breast, lung, colon, prostate, bladder