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Reduced expression of calsenilin/DREAM/KChIP3 in the brains of kainic acid-induced seizure and epilepsy patients

✍ Scribed by Yeon-Mi Hong; Dong-Gyu Jo; Min-Cheol Lee; So-Young Kim; Yong-Keun Jung


Book ID
117473623
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
145 KB
Volume
340
Category
Article
ISSN
0304-3940

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Kainic acid-induced seizures and brain d
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Seizure activity induced by kainic acid (KA) and subsequent neuronal death are thought to be associated with an increase in cytoplasmic free calcium ([Ca2+li) and can be prevented by N-methyl-D-aspartate (NMDA) antagonists. In addition to influx through receptor operated Ca2+ channels the increase i