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Reduced brain-derived neurotrophic factor is associated with a loss of serotonergic innervation in the hippocampus of aging mice

✍ Scribed by B. A. Luellen; L. E. Bianco; L. M. Schneider; A. M. Andrews

Book ID
111273087
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
388 KB
Volume
6
Category
Article
ISSN
1601-1848

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## Abstract Brain‐derived neurotrophic factor (BDNF) is involved in brain plasticity and neuronal survival. Generally, BDNF enhances synaptic activity and neurite growth, although the effect of BDNF on neuronal survival and brain plasticity following injury is equivocal. Housing rats in an enriched