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Reduced affinity of peripheral benzodiazepine binding sites in elderly insomniac patients

✍ Scribed by J. C. Gilbert; D. Valtier; R. Huguet; C. Hulin; J. P. Aquino; P. Meyer

Book ID
104797406
Publisher
Springer
Year
1988
Tongue
English
Weight
319 KB
Volume
34
Category
Article
ISSN
0031-6970

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Properties of benzodiazepine binding sit
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✍ L. Garau; M. A. M. Carai; W. Boi; M. G. Ennas; P. E. Manconi; P. F. Spano; M. Me πŸ“‚ Article πŸ“… 1989 πŸ› John Wiley and Sons 🌐 English βš– 426 KB

Benzodiazepine (BDZ) binding sites were studied by using 3H-diazepam and 3H-Ro 5-4864 in intact lymphocytes from peripheral blood (PBL), in comparison to kidney and cerebellum. Experiments with 3H-diazepam performed at equilibrium and measuring kinetics revealed that BDZ binding sites are indeed pre