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In situ molecular weight determination of brain and peripheral benzodiazepine binding sites

✍ Scribed by Steven M. Paul; Ellis S. Kempner; Phil Skolnick

Book ID
115876483
Publisher
Elsevier Science
Year
1981
Tongue
English
Weight
197 KB
Volume
76
Category
Article
ISSN
0014-2999

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Properties of benzodiazepine binding sit
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Benzodiazepine (BDZ) binding sites were studied by using 3H-diazepam and 3H-Ro 5-4864 in intact lymphocytes from peripheral blood (PBL), in comparison to kidney and cerebellum. Experiments with 3H-diazepam performed at equilibrium and measuring kinetics revealed that BDZ binding sites are indeed pre