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Reduced activities of key enzymes of gluconeogenesis as possible cause of acute toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in rats

✍ Scribed by Lutz W.D. Weber; Margitta Lebofsky; Bernhard U. Stahl; Joel R. Gorski; Giacomo Muzi; Karl Rozman

Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
843 KB
Volume
66
Category
Article
ISSN
0300-483X

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## Abstract The cancer bioassay for 2,3,7,8‐tetrachlorodibenzo‐__p__‐dioxin (TCDD) conducted by the Dow Chemical company in the mid 70s has been used extensively for conducting quantitative cancer risk assessments for human exposure to TCDD. More recently the National Toxicology Program (NTP) condu