## Abstract The cancer bioassay for 2,3,7,8โtetrachlorodibenzoโ__p__โdioxin (TCDD) conducted by the Dow Chemical company in the mid 70s has been used extensively for conducting quantitative cancer risk assessments for human exposure to TCDD. More recently the National Toxicology Program (NTP) condu
Subchronic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and their reversibility in male Sprague-Dawley rats
โ Scribed by Xuelin Li A; Karl K. Rozman
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 691 KB
- Volume
- 97
- Category
- Article
- ISSN
- 0300-483X
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๐ SIMILAR VOLUMES
Experiments were conducted to test the hypothesis that acute TCDD toxicity is associated with pituitary hypofunction. Sexually mature male Sprague-Dawley rats were given graded doses of TCDD (0-100 pglkg) and evaluated 7 days later. Despite pronounced hypophagia and body weight loss, plasma concentr
## Abstract 2,3,7,8โTetrachlorodibenzoโ__p__โdioxin (TCDD) is a potent immunosuppressant in several animal species. The purpose of this study was to determine if TCDD affected the activity of adenosine deaminase (ADA), a purine metabolizing enzyme that is vital to the proper functioning of the immu