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Redox regulation of p53 during hypoxia

✍ Scribed by Chandel, Navdeep S; Vander Heiden, Matthew G; Thompson, Craig B; Schumacker, Paul T

Book ID: 110064047
Publisher: Nature Publishing Group
Year: 2000
Tongue: English
Weight: 288 KB
Volume: 19
Category: Article
ISSN: 0950-9232
DOI: 10.1038/sj.onc.1203727

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## Abstract In response to various stresses, p53 is rapidly activated and transcriptionally regulates a number of target genes by which p53 modulates a variety of cellular activities. The transcriptional activity of p53 is delicately regulated by a plethora of cellular factors, independently or syn