Redox regulation of apoptotic cell death in the immune system
โ Scribed by Mark B Hampton; Sten Orrenius
- Book ID
- 119539688
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- English
- Weight
- 66 KB
- Volume
- 102-103
- Category
- Article
- ISSN
- 0378-4274
No coin nor oath required. For personal study only.
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## Abstract Apoptosis is a physiological mechanism allowing for the removal of abundant or potentially harmful cells. The hallmarks of apoptosis include degradation of cellular DNA, exposure of phosphatidylserine at the outer leaflet of the cell membrane and cell shrinkage. Phosphatidylserine expos
Cell death is an integral part of the functioning of the immune system. For T cells, potentially autoreactive or 'useless' cells are removed through apoptosis in response to signals (or lack of signals) from their T cell receptor complex. A myriad of proteins that can initiate or protect cells from