Recurrent trisomy 21: four cases in three generations
✍ Scribed by JL Gair; L Arbour; R Rupps; R Jiang; H Bruyère; WP Robinson
- Book ID
- 110888090
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 595 KB
- Volume
- 68
- Category
- Article
- ISSN
- 0009-9163
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📜 SIMILAR VOLUMES
Two cases of trisomy 12p due to a familial translocation t(12;21) (p11;p11) inherited through three generations are presented. The clinical features of both affected individuals are consistent with those previously reported. Study of the NORs by silver staining showed translocation of the NOR from c
The recurrence risk for Down syndrome (DS) is about 1% in case of a previous offspring with trisomy 21 and minimal in case of a de novo (21;21) translocation. We have monitored 1,211 pregnancies in the first and second trimester after a prior occurrence of trisomy 21. Six couples had a trisomy 21 fe