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Recurrent pleomorphic adenoma of the parotid gland: Analysis of 108 consecutive patients

✍ Scribed by Claus Wittekindt; Kristina Streubel; Georg Arnold; Eberhard Stennert; Orlando Guntinas-Lichius

Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
137 KB
Volume
29
Category
Article
ISSN
1043-3074

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✦ Synopsis

Abstract

Background

Surgery for recurrent parotid pleomorphic adenoma is a challenging problem.

Methods

One hundred eight patients who underwent 134 reoperations for recurrent parotid pleomorphic adenoma (follow‐up, 22 years) were evaluated for histopathologic features and risk factors for recurrence.

Results

The number of reoperations for tumor recurrence ranged from 1 to 10. Twenty‐seven patients (25%) developed permanent facial nerve weakness. The risks for clinically evident rerecurrence after 1, 5, and 15 years were 16%, 42%, and 75%, respectively. Female sex, young age at initial treatment, and enucleation instead of parotidectomy for treatment of the first recurrence were significant risk factors for rerecurrence. The mean number of recurrent tumor nodules was 26.

Conclusions

Surgery for recurrent parotid pleomorphic adenoma has a high rate of facial nerve morbidity. The chance of rerecurrence is high. Extended parotidectomy seems to be the best approach for the reoperation to reduce the risk of rerecurrence. Β© 2007 Wiley Periodicals, Inc. Head Neck 2007

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## Abstract ## Background. Pleomorphic adenoma constitutes the most common benign parotid gland tumor. Local recurrence after surgical treatment (lateral or total parotidectomy) has been described in 1% to 5% of cases. Malignant degeneration has been reported in 2% to 9% of cases of pleomorphic ad