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Recurrent Mutation of the Gene Encoding sequestosome 1 (SQSTM1/p62) in Paget Disease of Bone

✍ Scribed by Nancy Laurin; Jacques P. Brown; Jean Morissette; Vincent Raymond


Book ID
117853914
Publisher
American Society of Human Genetics
Year
2002
Tongue
English
Weight
324 KB
Volume
70
Category
Article
ISSN
0002-9297

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## Abstract Even though __SQSTM1__ gene mutations have been identified in a consistent number of patients, the etiology of Paget's disease of bone (PDB) remains in part unknown. In this study we analyzed __SQSTM1__ mutations in 533 of 608 consecutive PDB patients from several regions, including the