## Abstract ## BACKGROUND: Cleft lip with or without cleft palate (CLP) and cleft palate only (CPO) have an inherited component and, many studies suggest, a relationship with folate. Attempts to find folateβrelated genes associated with clefts have, however, often been inconclusive. This study exa
RECURRENCE RISKS FOR CLEFT LIP AND CLEFT PALATE IN BRITISH COLUMBIA INDIANS
β Scribed by Lowry, R.B.
- Book ID
- 123179859
- Publisher
- The Lancet
- Year
- 1970
- Tongue
- English
- Weight
- 146 KB
- Volume
- 296
- Category
- Article
- ISSN
- 0140-6736
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## Abstract **BACKGROUND:** The First Nations (Amerindian) population of British Columbia, Canada, has the highest reported birth prevalence in the world of cleft lip with or without cleft palate (CL/P) at nearly 3 per 1000 births. In addition, a substantial proportion of cleft palate only (CPO) ca
Nonsyndromic cleft lip with or without cleft palate (CL/P) is a common congenital malformation affecting about 1/1,000 caucasian infants. Although the familial clustering of CL/P has been studied thoroughly, estimation of recurrence risk for genetic counseling purposes can be difficult. A survey was