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Recurrence of nonalcoholic steatohepatitis (NASH) post-liver transplantation

✍ Scribed by McCaughan, G W


Publisher
Wiley (John Wiley & Sons)
Year
1997
Tongue
English
Weight
17 KB
Volume
3
Category
Article
ISSN
1074-3022

No coin nor oath required. For personal study only.

✦ Synopsis


I read with interest the two case reports 1,2 and editorial 3 on recurrence of nonalcoholic steatohepatitis (NASH) post-liver transplantation. Many of the interesting points were well made. However, I was amazed that there was no discussion about the possibility that neither of the 2 patients actually required liver transplantation in the first place.

Cirrhosis in NASH is well recognized, but liver failure is extremely uncommon. 4 It seems clear in the first case that liver failure was not present at the time of transplantation, and in the second, details of liver function before transplantation are not given. If recurrence of NASH is a common problem, perhaps a major lesson from the two cases is that stricter guidelines for indications for transplantation should be thought about in this disease.


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