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Recurrence of nonalcoholic steatohepatitis in a liver transplant recipient

โœ Scribed by Carson, K ;Washington, M K ;Treem, W R ;Clavien, P A ;Hunt, C M

Publisher
Wiley (John Wiley & Sons)
Year
1997
Tongue
English
Weight
180 KB
Volume
3
Category
Article
ISSN
1074-3022

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โœฆ Synopsis

A 42-year-old white man with morbid obesity and hypertriglyceridemia was noted to have nonalcoholic steatohepatitis (NASH) at the time of a laparoscopic cholecystectomy for presumed gallstone pancreatitis. His postoperative course was complicated by a 50-kg weight loss and continued right upper quadrant pain. Repeat liver biopsy revealed NASH with accompanying micronodular cirrhosis. Due to progressive fatigue, he underwent an orthotopic liver transplantation complicated by a 36-kg weight gain. Sixteen months posttransplantation, a liver biopsy revealed the recurrence of NASH. Screening for defects in fatty acid oxidation proved negative.

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