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RecQ helicases: multifunctional genome caretakers

โœ Scribed by Chu, Wai Kit; Hickson, Ian D.

Book ID
109948366
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
453 KB
Volume
9
Category
Article
ISSN
1474-1776

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The RecQ family of DNA helicases have been shown to be important for the maintenance of genomic integrity in all organisms analysed to date. In human cells, representatives of this family include the proteins defective in the cancer predisposition disorder Bloom's syndrome and the premature ageing c