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Defending genome integrity during S-phase: putative roles for RecQ helicases and topoisomerase III

โœ Scribed by Thomas J Oakley; Ian D Hickson


Book ID
117798821
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
642 KB
Volume
1
Category
Article
ISSN
1568-7864

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โœ Ronjon K. Chakraverty; Ian D. Hickson ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 140 KB

The RecQ family of DNA helicases have been shown to be important for the maintenance of genomic integrity in all organisms analysed to date. In human cells, representatives of this family include the proteins defective in the cancer predisposition disorder Bloom's syndrome and the premature ageing c