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Recovery of Proteolipid Protein in Mice Heterozygous for the Jimpy Gene

✍ Scribed by Joyce A. Benjamins; Diane M. Studzinski; Robert P. Skoff; Liljana Nedelkoska; Elizabeth A. Carrey; Charissa A. Dyer


Book ID
111175140
Publisher
John Wiley and Sons
Year
1989
Tongue
English
Weight
920 KB
Volume
53
Category
Article
ISSN
0022-3042

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Myelination in the jimpy mouse in the ab
✍ Dr. I.D. Duncan; J.P. Hammang; S. Goda; R.H. Quarles πŸ“‚ Article πŸ“… 1989 πŸ› John Wiley and Sons 🌐 English βš– 892 KB

A point mutation in the gene for proteolipid protein (PLP) has been suggested to account for the dysmyelination seen in the jimpy mouse mutant, Despite the absence of PLP, the major integral membrane protein of central nervous system (CNS) myelin, this study shows that there are many scattered myeli