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Recovery of normal hepatic glutathione levels lowered by acetaminophen in rat

โœ Scribed by A.I. Fiaschi; L. Micheli; G. Giorgi; F.M. Runci

Book ID
115886230
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
189 KB
Volume
183
Category
Article
ISSN
0014-2999

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Recovery of normal glutathione levels in
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The effect of a toxic dose of acetaminophen on hepatic glutathione turnover was studied in fed and fasted rats. Following the administration of 1 g m per kg of acetaminophen, the fractional rate of glutathione turnover increased from 0.19 to 0.28 hr-' in fed rats and from 0.43 to 0.50 hr-' in rats f