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Increased levels of hepatic metallothionein in rat and mouse after injection of acetaminophen

โœ Scribed by Uri Wormser; Daniel Calp


Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
346 KB
Volume
53
Category
Article
ISSN
0300-483X

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First-pass metabolism of acetaminophen i
โœ Junji Hirate; Chun-Yan Zhu; Isamu Horikoshi; Dr. Vijay O. Bhargava ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 373 KB ๐Ÿ‘ 2 views

The first-pass metabolism of acetaminophen was examined in rats after the administration of 15, 30, 150, and 300 mg kg-' doses by intra-arterial, intravenous, portal vein, and oral routes. Plasma concentrations of acetaminophen and its two major metabolites, acetaminophen glucuronide and acetaminoph