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Reconstitution of telomerase activity utilizing human catalytic subunit expressed in insect cells

✍ Scribed by Osamu Mikuni; James B Trager; Heidi Ackerly; Scott L Weinrich; Akira Asai; Yoshinori Yamashita; Tamio Mizukami; Hideharu Anazawa

Book ID: 117052737
Publisher: Elsevier Science
Year: 2002
Tongue: English
Weight: 275 KB
Volume: 298
Category: Article
ISSN: 0006-291X
DOI: 10.1016/s0006-291x(02)02417-8

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## BACKGROUND. Telomerase activation is thought to be crucial for the continued growth or progression of cancer cells. Three major subunits of human telomerase, human telomerase RNA (hTR), telomerase-associated protein (TP1), and human telomerase catalytic subunit (hTERT) have been identified rece