Recombinant Protein Drugs

✍ Scribed by Charles Weissmann (auth.), Peter Buckel (eds.)

Publisher: Birkhäuser Basel
Year: 2001
Tongue: English
Leaves: 206
Series: Milestones in Drug Therapy
Edition: 1
Category: Library

No coin nor oath required. For personal study only.

✦ Synopsis

Recombinant protein drugs are intimately associated with the impressive success story of the Biotech Industry during the past thirty years, some of them belonging to the most successful pharmaceutical products. More than thirty different proteins are available for a variety of clinical applications, over 300 proteins are presently being evaluated in clinical trials. In this new volume of the MDT series, historical, technical and clinical aspects of recombinant protein drug discovery and development are presented, covering past, present and future highlights. Leading scientists and co-founders of early Biotech companies describe technical breakthroughs and the fascinating story of pioneering discoveries, as well as the long way of translating them into products and business. Therefore, this book represents an exciting documentation of the beginning of a new era in the pharmaceutical industry. In addition, scientists from basic research, clinic and industry actively involved in new developments discuss...

✦ Table of Contents

Front Matter....Pages I-X
Front Matter....Pages 1-1
Recombinant interferon - the 20th anniversary....Pages 3-41
Combining science and business: from recombinant DNA to vaccines against hepatitis B virus....Pages 43-64
Front Matter....Pages 65-65
Clotting factors VIII and IX....Pages 67-88
Colony-stimulating factors: altering the practice of oncology....Pages 89-106
Tissue-type plasminogen activator: helping patients with acute myocardial infarction....Pages 107-126
Front Matter....Pages 127-127
Designing immunocytokines: genetically engineered fusion proteins for targeted immune therapy....Pages 129-147
Front Matter....Pages 149-149
Improving protein therapeutics: the evolution of the modern pharmacopoeia....Pages 151-168
Principles of gene transfer and foreign protein expression for human gene therapy....Pages 169-180
Back Matter....Pages 181-207

✦ Subjects

Medicine/Public Health, general

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