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Recombinant interleukin 2 (IL-2) promotes T cell line-mediated neuroautoimmune disease

✍ Scribed by H.J. Schluesener; H. Lassmann


Book ID
119106726
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
276 KB
Volume
11
Category
Article
ISSN
0165-5728

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A selected clone from an IL-2-dependent human T-cell line was persistently propagated in the presence of phorbol esters with the ability to activate protein kinase C (PKC), such as 12-0-tetradecanoylphorbol-I 3-acetate (TPA) or phorbol-12,1.3-dibutylate (PDBu). Thus, a TPA(PD6u)-dependent T-cell lin