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T-cell abnormalities in inflammatory bowel disease are mediated by interleukin 2

โœ Scribed by Ellen C. Ebert; Scott H. Wright; William H. Lipshutz; Stephen P. Hauptman

Book ID
118374357
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
916 KB
Volume
33
Category
Article
ISSN
1090-2341

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## Background: We previously demonstrated that in inflammatory bowel disease (IBD) there is enhanced production of interleukin (IL)-21, a cytokine that activates multiple pathways that sustain mucosal inflammation. However, the phenotype of IL-21-producing cells in IBD, and the cytokine(s) they cop