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Recombinant human interleukin-1β and its muteins

✍ Scribed by Y. Kikumoto; T. Kamogashira; Y.-M. Hong; S. Nakai; Y. Masui; Y. Hirai


Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
112 KB
Volume
10
Category
Article
ISSN
0192-0561

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Both interleukin-1 alpha (IL-1 alpha) and interleukin-1 beta (IL-1 beta) are powerful stimulators of bone resorption in vivo and in vitro. Interleukin-1 receptor antagonist (IL-1ra) binds to many interleukin-1 receptors. It does not activate the receptor and effectively blocks the action of IL-1 alp