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Recombinant human erythropoietin increases the radiosensitivity of xenografted human tumours in anaemic nude mice

✍ Scribed by G. Stüben; O. Thews; C. Pöttgen; K. Knühmann; P. Vaupel; M. Stuschke


Book ID
106124594
Publisher
Springer-Verlag
Year
2001
Tongue
English
Weight
94 KB
Volume
127
Category
Article
ISSN
1432-1335

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The blood kinetics and tissue distribution of a conjugate of daunomycin and a monoclonal antibody (791T/36) have been examined in mice, including nude mice with human tumour xenografts reactive with the antibody. For this the antibody moiety of the conjugate was labelled with 125I and the drug moiet