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Recombinant Adenovirus: A Gene Transfer Vector for Study and Treatment of CNS Diseases

✍ Scribed by Beverly L. Davidson; Martha C. Bohn

Book ID: 115606474
Publisher: Elsevier Science
Year: 1997
Tongue: English
Weight: 67 KB
Volume: 144
Category: Article
ISSN: 0014-4886
DOI: 10.1006/exnr.1996.6398

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## Abstract ## Background Brain‐directed prenatal gene therapy may benefit some lysosomal storage diseases that affect the central nervous system (CNS) before birth. Our previous study showed that intrauterine introduction of recombinant adenoviruses into cerebral ventricles results in efficient g