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Adenovirus-mediated gene transfer of the HSV-thymidine kinase gene for the treatment of primary CNS malignancies

โœ Scribed by S.L. Eck; J. Smith; E. Wheeldon; D. Smith; D. Hackney; S. Raper

Book ID
116167782
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
146 KB
Volume
31
Category
Article
ISSN
0959-8049

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lacZ gene driven by the b-actin -based promoter. Ex-SEE EDITORIAL ON PAGE 1696. pression of the HSVtk gene by adenovirus from AFP promoter/enhancer (AdAFPtk) induced the cells sensitive to ganciclovir (GCV) in the AFP-producing cell We have developed a recombinant replication-deline efficiently, but