✦ LIBER ✦

Recognizing and avoiding siRNA off-target effects for target identification and therapeutic application

✍ Scribed by Jackson, Aimee L.; Linsley, Peter S.

Book ID: 109950941
Publisher: Nature Publishing Group
Year: 2010
Tongue: English
Weight: 448 KB
Volume: 9
Category: Article
ISSN: 1474-1776
DOI: 10.1038/nrd3010

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Detecting microRNA binding and siRNA off

Detecting microRNA binding and siRNA off-target effects from expression data

✍ van Dongen, Stijn (author);Abreu-Goodger, Cei (author);Enright, Anton J. (author 📂 Article 📅 2008 🏛 Nature Publishing Group 🌐 English ⚖ 1024 KB

Detecting microRNA binding and siRNA off

Detecting microRNA binding and siRNA off-target effects from expression data

✍ van Dongen, Stijn (author);Abreu-Goodger, Cei (author);Enright, Anton J. (author 📂 Article 📅 2008 🏛 Nature Publishing Group 🌐 English ⚖ 1024 KB

Chemical-protein interactome and its app

Chemical-protein interactome and its application in off-target identification

✍ Lun Yang; Ke-Jian Wang; Li-Shan Wang; Anil G. Jegga; Sheng-Ying Qin; Guang He; J 📂 Article 📅 2011 🏛 International Association of Scientists in the Int 🌐 English ⚖ 199 KB

Engineering RNA for Targeted siRNA Deliv

Engineering RNA for Targeted siRNA Delivery and Medical Application

✍ Peixuan Guo; Oana Coban; Nicholas M. Snead; Joe Trebley; Steve Hoeprich; Songchu 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 362 KB

Comparative assessment of siRNA and shRN

Comparative assessment of siRNA and shRNA off target effects: what is slowing clinical development

✍ Rao, D D; Senzer, N; Cleary, M A; Nemunaitis, J 📂 Article 📅 2009 🏛 Nature Publishing Group 🌐 English ⚖ 132 KB

Application of mass spectrometry for tar

Application of mass spectrometry for target identification and characterization

✍ Joseph A. Loo; Dana E. DeJohn; Ping Du; Tracy I. Stevenson; Rachel R. Ogorzalek 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 175 KB 👁 2 views

Mass spectrometry-based methodologies span the vast expanse of drug discovery. Both electrospray ionization (ESI) and matrix-assisted laser desorption/ionization (MALDI) support proteomics-based research projects by identifying proteins separated and isolated by polyacrylamide gel electrophoresis. M