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Recognition of the Peripheral Self by Naturally Arising CD25+ CD4+ T Cell Receptors

โœ Scribed by Chyi-Song Hsieh; Yuqiong Liang; Aaron J. Tyznik; Steven G. Self; Denny Liggitt; Alexander Y. Rudensky

Book ID
116570326
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
359 KB
Volume
21
Category
Article
ISSN
1074-7613

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๐Ÿ“œ SIMILAR VOLUMES

Specificity of regulatory CD4+CD25+ T ce
Specificity of regulatory CD4+CD25+ T cells for self-T cell receptor determinants
โœ Abigail C. Buenafe; Laura Tsaknaridis; Leslie Spencer; Kevin S. Hicks; Rachel H. ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 445 KB

## Abstract Although the phenotypic and regulatory properties of the CD4^+^CD25^+^ T cell lineage (Treg cells) have been well described, the specificities remain largely unknown. We demonstrate here that the CD4^+^CD25^+^ Treg population includes the recognition of a broad spectrum of human TCR CDR