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Cutting Edge: Self-Peptides Drive the Peripheral Expansion of CD4+CD25+ Regulatory T Cells

✍ Scribed by Cozzo, C.; Larkin, J.; Caton, A. J.

Book ID: 127262016
Publisher: American Association of Immunologists
Year: 2003
Tongue: English
Weight: 637 KB
Volume: 171
Category: Article
ISSN: 0022-1767
DOI: 10.4049/jimmunol.171.11.5678

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## Abstract Although the phenotypic and regulatory properties of the CD4^+^CD25^+^ T cell lineage (Treg cells) have been well described, the specificities remain largely unknown. We demonstrate here that the CD4^+^CD25^+^ Treg population includes the recognition of a broad spectrum of human TCR CDR