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Recognition of DNA Base Mismatches by a Rhodium Intercalator

✍ Scribed by Jackson, Brian A.; Barton, Jacqueline K.

Book ID
125853539
Publisher
American Chemical Society
Year
1997
Tongue
English
Weight
101 KB
Volume
119
Category
Article
ISSN
0002-7863

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## Abstract An electrochemical approach for single base‐specific detection of label‐free target single‐strand DNA (ssDNA) was demonstrated. The approach was based on the high ligation selectivity of __Taq__ DNA ligase coupled with ferrocenated gold nanoparticle/streptavidin conjugate‐based voltamme