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Recognition of DMA methylation by zinc fingers

✍ Scribed by Choo, Yen


Book ID
109964756
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
424 KB
Volume
5
Category
Article
ISSN
1072-8368

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Zinc fingers, 30-residue peptides anchored on Zn(II) coordinated to pairs of cysteines and histidines, recognize DNA triplets and, as tandem modules, effect sequence read out. The focus of zinc finger-DNA interaction studies thus far has been to probe the nature of the binding of the 12-residue reco