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Reciprocal regulation of microRNA-122 and c-Myc in hepatocellular cancer: Role of E2F1 and transcription factor dimerization partner 2

✍ Scribed by Wang, Bo; Hsu, Shu-hao; Wang, Xinmei; Kutay, Huban; Bid, Hemant Kumar; Yu, Jianhua; Ganju, Ramesh K.; Jacob, Samson T.; Yuneva, Mariia; Ghoshal, Kalpana


Book ID
121737284
Publisher
John Wiley and Sons
Year
2013
Tongue
English
Weight
922 KB
Volume
59
Category
Article
ISSN
0270-9139

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## Abstract Phosphatidylinositol 3‐kinase (PI3K) signaling controls survival and proliferation of cancer cells and is activated in around 60% of pancreatic ductal adenocarcinomas (PDACs). Although not entirely clarified, PI3K signaling is linked to cell cycle progression of PDAC cells. In this stud