90. Recherches sur la formation et la transformation des esters LIX [l] Sur la preparation de monoesters sulfuriques d'amino-alcools et sur leur scission par Emile Cherbuliez, S1. Colak-AntiC, G. Wyss et J. Rabinowitz (31. 111. 65) A. -Nous avons prCpar6 quelques nouveaux monoesters sulfuriques d'
Recherches sur la formation et la transformation des esters XLVIII. Sur la préparation de monoesters phosphoniques d'amino-alcools et sur leur quaternisation
✍ Scribed by Emile Cherbuliez; A. Gabbai; M. Gowhari; J. Rabinowitz
- Publisher
- John Wiley and Sons
- Year
- 1963
- Tongue
- German
- Weight
- 380 KB
- Volume
- 46
- Category
- Article
- ISSN
- 0018-019X
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✦ Synopsis
Abstract
Amino alcohols containing a primary, a secondary or a tertiary amino group, yield with phenylphosphonic oxide the corresponding aminoalkyl phenylphosphonic monoesters.
📜 SIMILAR VOLUMES
## Abstract Phosphorous monoesters of amino alcohols are obtained by heating equimolecular amounts of phosphorous acid and the corresponding amino alcohol at 150–200°, under reduced pressure.
Phosphorous acid does not dehydrate tertiary alcohols at temperatures below 100 "C ; but the esterification reaction is very slow and phosphorous monoesters of tertiary alcohols cannot be obtained this way. Although this reaction is also slow with phenol, phenyl phosphorous monoester can be obtained
Treated with a primary or secondary alcohol, phenylphosphonic oxide (C~6~H~5~PO~2~)~n~ gives the corresponding phosphonic monoesters in very good yield.
## Abstract Poly‐cyclohexanephosphonic acid is obtained very easily by heating cyclohexanephosphonic acid, under reduced pressure, at 180–190°C, for 96 to 150 hours.
## Abstract The synthesis and the rate of scission of some new cyanoalkyl‐phosphoric monoesters are described. In the case of β‐cyanoalkyl‐phosphoric monoesters, the monoester group is no more dephosphorylated in alkaline medium when the two H in the β position are substituted by alkyl groups.