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Receptor state and ligand efficacy: Two-state model of receptor activity does not explain ligand efficacy

✍ Scribed by Peter Chidiac


Book ID
117340819
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
305 KB
Volume
16
Category
Article
ISSN
0165-6147

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Signaling through G-protein coupled receptors is one of the most prevalent and important methods of transmitting information to the inside of cells. Many mathematical models have been proposed to describe this type of signal transduction, and the ternary complex (ligand/receptor/G-protein) model and