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Modulation of Opioid Receptor Ligand Affinity and Efficacy Using Active and Inactive State Receptor Models

✍ Scribed by Jessica P. Anand; Lauren C. Purington; Irina D. Pogozheva; John R. Traynor; Henry I. Mosberg


Book ID
117940188
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
363 KB
Volume
80
Category
Article
ISSN
1747-0277

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Signaling through G-protein coupled receptors is one of the most prevalent and important methods of transmitting information to the inside of cells. Many mathematical models have been proposed to describe this type of signal transduction, and the ternary complex (ligand/receptor/G-protein) model and