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Receptor-mediated therapeutic transport across the blood–brain barrier

✍ Scribed by Wang, Yun-Yan; Lui, Philip CW; Li, Jian Yi


Book ID
120504078
Publisher
Future Medicine
Year
2009
Tongue
English
Weight
744 KB
Volume
1
Category
Article
ISSN
1750-743X

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The perfusion of rat brain with '251-transferrin resulted in a receptor-mediated uptake of transferrin into the endothelium of the blood-brain barrier followed by its detection in the brain. During a pulsechase experiment, lZSI-transferrin accumulated in the endothelial cells during the pulse, with