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Receptor-mediated endocytosis of tissue-type plasminogen activator (t-PA) by liver cells

✍ Scribed by D.C. Rijken; M. Otter; J. Kuiper; Th.J.C. van Berkel

Book ID
119037903
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
622 KB
Volume
57
Category
Article
ISSN
0049-3848

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Full-length tissue-type plasminogen activator (t-PA) cDNA served to construct deletion mutants within the N-terminal "heavy" (H)-chain of the t-PA molecule. The H-chain cDNA consists of an array of structural domains homologous to domains present on other plasma proteins ("finger, " "epidermal growt