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Functional characterization of a monoclonal anti tissue type plasminogen activator (t-PA) antibody stimulating plasminogen activator activity of t-PA

✍ Scribed by J. Wojta; R. Beckmann; L. Turcu; B.R. Binder


Book ID
119036302
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
99 KB
Volume
41
Category
Article
ISSN
0049-3848

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Full-length tissue-type plasminogen activator (t-PA) cDNA served to construct deletion mutants within the N-terminal "heavy" (H)-chain of the t-PA molecule. The H-chain cDNA consists of an array of structural domains homologous to domains present on other plasma proteins ("finger, " "epidermal growt