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Receptor mechanisms mediating differentiation and proliferation effects of retinoids on neuroblastoma cells

✍ Scribed by Q. Campbell Hewson; P.E. Lovat; A.J. Malcolm; A.D.J. Pearson; C.P.F. Redfern

Book ID
117478322
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
232 KB
Volume
279
Category
Article
ISSN
0304-3940

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The cytotoxic effects of retinoids on neuroblastoma cells at various times during electrophysiological differentiation were evaluated. We used NIE-115, a clone of the murine neuroblastoma C1300 derived from the neural crest, and three retinoids: vitamin A (retinol), all-trans retinoic acid (tretinoi