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Receptor-interacting protein 140 interacts with and inhibits transactivation by, peroxisome proliferator-activated receptor α and liver-X-receptor α

✍ Scribed by Kenji S. Miyata; Shannon E. McCaw; Lisa M. Meertens; Hansa V. Patel; Richard A. Rachubinski; John P. Capone

Book ID: 117464084
Publisher: Elsevier Science
Year: 1998
Tongue: English
Weight: 231 KB
Volume: 146
Category: Article
ISSN: 0303-7207
DOI: 10.1016/s0303-7207(98)00196-8

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## Abstract The peroxisome proliferator‐activated receptor‐α (PPAR‐α) plays a key role in lipid metabolism and inflammation. Recently, we demonstrated that administration of the PPAR‐α agonists gemfibrozil and fenofibrate, inhibit the clinical signs of experimental autoimmune encephalomyelitis (EAE