Recent Syntheses of Pyrazolo[3,4-d]pyrimidine Ring Systems
✍ Scribed by Qun Dang
- Publisher
- John Wiley and Sons
- Year
- 2005
- Weight
- 8 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0931-7597
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## Abstract Pyrazolo‐[3,4‐__d__]pyrimidine‐4,6‐diones **5** and pyrazolo[4,3‐__d__]pyrimidine‐5,7‐diones **7** were synthesized by Curtius rearrangement of pyrazolic mono‐esters **2** and **3** followed by hetero‐cyclization __via__ the ureas derivatives **4** and **6** under alkaline conditions.
## Abstract magnified image A series of pyrazolo[3,4‐__b__]pyridines has been synthesized by __Friedländer__ condensation of 5‐amino‐pyrazole‐4‐carbaldehyde **1** with active methylene compounds in basic medium. Pyrazolo[4′3′:5,6]pyrido‐[2,3‐__d__]pyrimidines have been synthesized from pyrazolo[3,
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