✦ LIBER ✦

Recent progress in the theoretical treatment of protein folding

✍ Scribed by Harold A. Scheraga

Publisher: Wiley (John Wiley & Sons)
Year: 1983
Tongue: English
Weight: 814 KB
Volume: 22
Category: Article
ISSN: 0006-3525
DOI: 10.1002/bip.360220104

No coin nor oath required. For personal study only.

✦ Synopsis

The multiple-minima problem encountered in computations of the conformational energy of a globular protein can be approached by extending, in part, the methodology used heretofore to treat small oligopeptides and fibrous proteins, and by incorporating procedures to treat short., medium, and long-range interactions. The latter consist primarily of energy minimization and application of distance constraints. Initial tests with the 20-residue membrane-bound portion of melittin and with the 58-residue bovine pancreatic trypsin inhibitor are sufficiently encouraging to suggest that the potential functions and computational algorithms are reasonable and extendable to globular proteins containing as many as 200 amino acid residues.

📜 SIMILAR VOLUMES

Recent progress in the treatment of tube

Recent progress in the treatment of tuberculosis

📂 Article 📅 1923 🏛 Wiley (John Wiley & Sons) ⚖ 237 KB

proccss '' kilns. Ti1 otlicr words, tlic licnt hi gnscs a t nhoiit 900' C. is iiiorc cnicicntly iitiliscd tlinti tlic siitiic ntiioant of licnt in t1oul)lc tlic quantity of gnses at, say, 500° C. Still, wnstclirnt, r c c o \ -t ~~\* hoilcrs arc in successful illid protitnblc opcrntioti with tlic cnt

Recent progress and new trends in the tr

Recent progress and new trends in the treatment of hepatitis B

✍ Alfredo Alberti; Maurizia Rossana Brunetto; Massimo Colombo; Antonio Craxì 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 69 KB

## Abstract The annual rate of progression to cirrhosis in patients with chronic HBV is 0.4 to 14.2% and that of death 4 to 10%. HCC risk increases in parallel with the severity and duration of infection, with an annual incidence less than 0.5% in carriers and 6% in patients with cirrhosis. The mai

Numerical comparisons of three recently

Numerical comparisons of three recently proposed algorithms in the protein folding problem

✍ Hansmann, Ulrich H. E.; Okamoto, Yuko 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 300 KB 👁 1 views

We numerically compare the effectiveness of three recently proposed algorithms, multicanonical algorithm, simulations in a 1rk-sampling, and simulated tempering, for the protein folding problem. We perform simulations with high statistics for one of the simplest peptides, met-enkephalin. While the p

Recent Progress in the Chemistry of Azaa

Recent Progress in the Chemistry of Azaazulenes.

✍ Noritaka Abe 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 23 KB 👁 2 views

Recent Progress in the Synthesis of Epot

Recent Progress in the Synthesis of Epothilones

✍ Ruzhou Zhang; Zhiyu Liu 📂 Article 📅 2004 🏛 John Wiley and Sons ⚖ 53 KB 👁 3 views

Recent Progress in the Synthesis of Quin

Recent Progress in the Synthesis of Quinolines

✍ Vladimir V. Kouznetsov; Leonor Y. Vargas Mendez; Carlos M. Melendez Gomez 📂 Article 📅 2005 🏛 John Wiley and Sons ⚖ 8 KB 👁 3 views