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Numerical comparisons of three recently proposed algorithms in the protein folding problem

✍ Scribed by Hansmann, Ulrich H. E.; Okamoto, Yuko


Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
300 KB
Volume
18
Category
Article
ISSN
0192-8651

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✦ Synopsis


We numerically compare the effectiveness of three recently proposed algorithms, multicanonical algorithm, simulations in a 1rk-sampling, and simulated tempering, for the protein folding problem. We perform simulations with high statistics for one of the simplest peptides, met-enkephalin. While the performances of all three approaches is much better than traditional methods, we find that the differences among the three are only marginal.