Medical treatment of osteogenesis imperf
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Horacio Plotkin; Francis H. Glorieux
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Article
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2000
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John Wiley and Sons
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English
โ 70 KB
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Osteogenesis imperfecta (OI) comprises a group of disorders principally affecting type I collagen which result in increased bone fragility. Children with severe OI suffer recurrent fractures, resulting in severe deformity and growth stunting in many cases, with loss of independent ambulation by the