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Recent developments in drug resistance mechanism in chronic myeloid leukemia: a review

✍ Scribed by Shantashri Vaidya; Kanjaksha Ghosh; Babu Rao Vundinti

Book ID: 114795411
Publisher: John Wiley and Sons
Year: 2011
Tongue: English
Weight: 298 KB
Volume: 87
Category: Article
ISSN: 0902-4441
DOI: 10.1111/j.1600-0609.2011.01689.x

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## BACKGROUND. Overexpression of the multidrug resistance gene (MDR1) product, the MDR1 protein (MDR1), has been associated with poor prognosis in several hematologic malignancies. The significance of MDR1 levels in patients with chronic myeloid leukemia (CML) has not been established. ## METHODS