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Recent advances in the use of protein transduction domains for the delivery of peptides, proteins and nucleic acids invivo

โœ Scribed by Snyder, Eric L; Dowdy, Steven F

Book ID
120436921
Publisher
Informa plc
Year
2005
Tongue
English
Weight
357 KB
Volume
2
Category
Article
ISSN
1742-5247

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Gene delivery using a derivative of the
Gene delivery using a derivative of the protein transduction domain peptide, K-Antp
โœ Sang-Hyun Min; Dong Min Kim; Mi Na Kim; Jiang Ge; Dong Chul Lee; In Young Park; ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 580 KB

Due to their intracellular permeability, protein transduction domains (PTDs) have been widely used to deliver proteins and peptides to mammalian cells. However, their performance in gene delivery has been relatively poor. To improve the efficiency of PTD-mediated gene delivery, we synthesized a new