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Recent advances in gene expression using alphavirus vectors

✍ Scribed by Henrik Garoff; Ke-Jun Li

Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
469 KB
Volume
9
Category
Article
ISSN
0958-1669

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✦ Synopsis

Alphavirus vectors use RNA replication in the cell cytoplasm to direct gene expression. New developments of vectors put persistency of expression and infection of specific cells in focus. Furthermore, a new application shows that the system can be used for production of retrovirus vectors carrying genes with introns and control/regulatory regions.

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