## Recent advances in capillary electrophoresis-based proteomic techniques for biomarker discovery A compelling need exists for the development of technologies that facilitate and accelerate the discovery of novel protein biomarkers with therapeutic and diagnostic potential. The inherent disadvant
Recent advances in capillary electrophoresis for biomarker discovery
✍ Scribed by Rania Bakry; Christian W. Huck; Muhammed Najam-ul-Haq; Matthias Rainer; Günther K. Bonn
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 619 KB
- Volume
- 30
- Category
- Article
- ISSN
- 1615-9306
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✦ Synopsis
Abstract
The use of non‐invasive methods for detecting biomarkers opens a new era in patient care, since clinical investigators have long been searching for accurate and reproducible measurements of putative biomarkers. There are many factors which make this research challenging, beginning with lack of standardization of sample collection and continuing through the entire analytical procedure. Among the variety of methods so far used for biomarker screening, capillary electrophoresis represents a robust, reliable, and widely used analytical tool. This review will focus on recent applications of CE to the analysis of body fluids and tissues for identification of biomarkers.
📜 SIMILAR VOLUMES
Papers detailing the use of affinity capillary electrophoresis (ACE) in examining binding parameters between biological species are summarized in this review. The works cited in this review were published during 2007 and were drawn from the major chemical and biochemical journals and especially the